TREAT-AD Portfolio Dashboard

TREAT-AD Portfolio Dashboard

Gene

Contributing TREAT-AD Center

Bioinformatic analysis

Target assessment

Antibody validation

Protein constructs

Crystal structure

Screening

Biochemical assay

Biophysical assay

Cell-based assay

Chemical Probes

Biological Probe

In vivo Probes

Biomarkers

AD Informer Set (Chemical probe available)

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1

IUSM-Purdue

n/a

n/a

n/a

n/a

n/a

2

IUSM-Purdue

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

3

IUSM-Purdue

n/a

4

IUSM-Purdue

n/a

n/a

5

NEK7

IUSM-Purdue

n/a

n/a

n/a

n/a

6

IUSM-Purdue

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

7

PIK3C2A

IUSM-Purdue

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

8

IUSM-Purdue

n/a

n/a

9

IUSM-Purdue

n/a

n/a

n/a

10

PTPN6 (aka SHP1)

IUSM-Purdue

n/a

n/a

n/a

11

IUSM-Purdue

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

12

AP2A2

Emory-Sage-SGC-JAX

13

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

14

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

15

Emory-Sage-SGC-JAX

n/a

n/a

16

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

17

BIN1

Emory-Sage-SGC-JAX

n/a

18

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

19

Emory-Sage-SGC-JAX

n/a

20

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

21

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

22

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

23

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

24

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

25

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

26

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

27

Emory-Sage-SGC-JAX

n/a

n/a

28

Emory-Sage-SGC-JAX

n/a

n/a

29

DLAT

Emory-Sage-SGC-JAX

30

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

31

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

32

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

33

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

34

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

35

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

36

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

37

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

38

Emory-Sage-SGC-JAX

n/a

n/a

n/a

39

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

40

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

41

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

42

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

43

NRN1

Emory-Sage-SGC-JAX

44

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

45

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

46

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

47

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

48

Emory-Sage-SGC-JAX

n/a

n/a

49

PDHA1

Emory-Sage-SGC-JAX

50

PDHB

Emory-Sage-SGC-JAX

51

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

52

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

53

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

54

PSMC3

Emory-Sage-SGC-JAX

n/a

n/a

n/a

55

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

56

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

57

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

58

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

59

Emory-Sage-SGC-JAX

n/a

60

Emory-Sage-SGC-JAX

61

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

62

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

63

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

64

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

65

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

66

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

67

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

68

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

69

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

70

Emory-Sage-SGC-JAX

n/a

71

Emory-Sage-SGC-JAX

n/a

n/a

72

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

73

74

75

76

77

78

79

80

81

82

83

84

85

86

87

88

89

90

91