TREAT-AD Portfolio Dashboard

TREAT-AD Portfolio Dashboard

Gene

Contributing TREAT-AD Center

Bioinformatic analysis

Antibody validation

Protein constructs

Crystal structure

Screening

Biochemical assay

Biophysical assay

Cell-based assay

Chemical Probes

In vivo Probes

Biomarkers

AD Informer Set (Chemical probe available)

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1

IUSM-Purdue

2

IUSM-Purdue

n/a

3

IUSM-Purdue

n/a

4

PTPN6 (aka SHP1)

IUSM-Purdue

n/a

n/a

5

AP2A2

Emory-Sage-SGC-JAX

6

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

7

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

8

Emory-Sage-SGC-JAX

n/a

9

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

10

BIN1

Emory-Sage-SGC-JAX

n/a

11

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

12

Emory-Sage-SGC-JAX

13

Emory-Sage-SGC-JAX

n/a

n/a

n/a

14

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

15

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

16

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

17

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

18

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

19

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

20

Emory-Sage-SGC-JAX

n/a

21

DHX58

Emory-Sage-SGC-JAX

n/a

22

DLAT

Emory-Sage-SGC-JAX

23

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

24

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

25

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

26

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

27

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

28

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

29

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

30

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

31

IFIH1

Emory-Sage-SGC-JAX

n/a

32

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

33

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

34

Emory-Sage-SGC-JAX

n/a

n/a

n/a

35

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

36

NRN1

Emory-Sage-SGC-JAX

37

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

38

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

39

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

40

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

41

Emory-Sage-SGC-JAX

n/a

n/a

42

PDHA1

Emory-Sage-SGC-JAX

43

PDHB

Emory-Sage-SGC-JAX

44

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

45

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

46

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

47

PSMC3

Emory-Sage-SGC-JAX

n/a

n/a

n/a

48

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

49

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

50

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

51

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

52

Emory-Sage-SGC-JAX

n/a

53

Emory-Sage-SGC-JAX

54

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

55

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

56

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

57

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

58

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

59

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

60

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

61

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

62

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

63

Emory-Sage-SGC-JAX

64

Emory-Sage-SGC-JAX

n/a

65

Emory-Sage-SGC-JAX

n/a

n/a

n/a

n/a

n/a

n/a

n/a

n/a

66

67

68

69

70

71

72

73

74

75

76

77

78

79

80

81

82

83

84