| 1 | | Pathology | | | akneumann@salud.unm.edu | Fungal pathogen cell wall structure, Innate immune fungal recognition--cell biology and signal transduction. | 0 | 0 | 0 | 1 maybe | Yes | | | Undecided | http://www.ncbi.nlm.nih.gov/sites/myncbi/1ZQ6vr51eqoQO/bibliograpahy/46671725/public/?sort=date&direction=ascending |
| 2 | | Pharmaceutical Sciences | | https://hsc.unm.edu/pharmacy/research/areas/cmbm/projects.html | ambolt@salud.unm.edu | Metals Toxicology, Immunotoxicology
The current research interests of the lab are on determining the molecular mechanisms of how environmental metals can advance tumor progression by targeting the surround tumor microenvironment and how mixed metal exposures leads to immune dysfunction. | | Maybe 1 PhD | 2 | 1 | Yes | Yes | | Yes | https://pubmed.ncbi.nlm.nih.gov/34865172/
https://pubmed.ncbi.nlm.nih.gov/34498067/
https://pubmed.ncbi.nlm.nih.gov/33146397/
https://pubmed.ncbi.nlm.nih.gov/32710956/
https://pubmed.ncbi.nlm.nih.gov/25324207/ |
| 3 | | Molecular Genetics and Microbiology | | www.thekelllab.org | amkell@salud.unm.edu | virus-host interactions, viral pathogenesis, innate immunity, inflammation | | 1 PhD | 2 | 1 | Yes | Yes | yes | | https://pubmed.ncbi.nlm.nih.gov/?term=Kell%20AM&cauthor_id=25749629 |
| 4 | | Department of Pharmaceutical Sciences, College of Pharmacy | | https://hsc.unm.edu/directory/barkley-levenson-amanda.html | abarkleylevenson@salud.unm.edu | Behavioral genetics; behavioral neuroscience; alcohol use disorders and related psychiatric disorders | | No MS
No PhD | 0 | 1 PhD or MS | Yes | Yes | | No | 1. https://onlinelibrary.wiley.com/doi/10.1111/gbb.12760
Zhou, X., Barkley-Levenson, A., Montilla-Perez, P., Telese, F., & Palmer, A.A. (2021) Functional validation of a finding from a mouse genome-wide association study demonstrates that a mutant allele of Azi2 alters sensitivity to methamphetamine. Genes Brain Behavior 20 (7): e12760. doi: 10.1111/gbb.12760.
2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311926/
Baud, A., Casale, F.P., Barkley-Levenson, A.M., Farhadi, N., Montillot, C., Yalcin, B., Nicod, J., Palmer, A.A., & Stegle, O. (2021) Dissecting indirect genetic effects from peers in laboratory mice. Genome Biology 22(1): 216. doi: 10.1186/s13059-021-02415-x.
3.https://pubmed.ncbi.nlm.nih.gov/33556460/
Savarese, A.M., Ozburn, A.R., Barkley-Levenson, A.M., Metten, P., & Crabbe, J.C. (2021) The impact of Drinking in the Dark (DID) procedural manipulations on ethanol intake in High Drinking in the Dark (HDID) mice. Alcoholism Clinical and Experimental Research 93: 45-56. doi: 10.1016/j.alcohol.2021.02.001.
4.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835754/
Barkley-Levenson, A. M., Lee, A., & Palmer, A. A. (2021) Genetic and pharmacological manipulations of glyoxalase 1 mediate ethanol withdrawal seizure susceptibility in mice. Brain Sciences 11(1): 127. doi: 10.3390/brainsci11010127.
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939988/
Barkley-Levenson, A.M., Der-Avakian, A., & Palmer, A.A. (2020) Assessing the motivational effects of ethanol in mice using a discrete-trial current-intensity intracranial self-stimulation procedure. Drug and Alcohol Dependence 207: 107806. doi: 10.1016/j.drugalcdep.2019.107806. |
| 5 | | Cell Biology and Physiology | UNM Comprehensive Cancer Center | https://hsc.unm.edu/directory/gardiner-amy.html | agardiner@salud.unm.edu | Neurodevelopment, prenatal alcohol exposure, cancer biology, angiogenesis
Post-transcriptional regulation, RNA-binding proteins, non-coding RNAs | 0 | 0
Maybe 0 – 1 PhD | 1 | 1 | Yes | Yes | | No | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722592/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9262970/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8151252/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329534/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693437/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064884/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495632/ |
| 6 | | Pathology | | https://hsc.unm.edu/medicine/departments/pathology/research/labs/wandinger-ness.html | awandinger-ness@salud.unm.edu | Rac1 and Cdc42 GTPases as therapeutic targets in ovarian cancer. Collaborative work with the Hudson lab is focused on cell, animal and entrepreneurial studies to improve treatment options for patients. | 0 | 1 | 2 | 1 | Yes | | | Yes | The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo.
Grimes MM, Kenney SR, Dominguez DR, Brayer KJ, Guo Y, Wandinger-Ness A, Hudson LG.
BMC Cancer. 2021 Jan 7;21(1):40. doi: 10.1186/s12885-020-07716-1.
PMID: 33413202
Dual Actions of Ketorolac in Metastatic Ovarian Cancer.
Hudson LG, Cook LS, Grimes MM, Muller CY, Adams SF, Wandinger-Ness A.
Cancers (Basel). 2019 Jul 24;11(8):1049. doi: 10.3390/cancers11081049.
PMID: 31344967
Ovarian Tumor Microenvironment Signaling: Convergence on the Rac1 GTPase.
Hudson LG, Gillette JM, Kang H, Rivera MR, Wandinger-Ness A.
Cancers (Basel). 2018 Sep 27;10(10):358. doi: 10.3390/cancers10100358. |
| 7 | | Department of Cell Biology & Physiology | UNMCCC | https://scholar.google.co.in/citations?user=67NTIdwAAAAJ&hl=en | aganesan@salud.unm.edu | Research topics: Long non-coding RNA (lncRNAs), Epigenetics, Chromatin Biology.
Active research areas:
1. Role of oncogenic lncRNAs in genetic and epigenetic regulation and cancer progression.
2. LncRNA chromatin (enhancer-promoter) interactions in cancer cells.
3. Whether/how extrachromosomal circular DNA (eccDNA) hub formation and lncRNA interactions enhance cancer progression and therapy resistance.
4. Biophysical approach to study the physical properties of human mitotic chromosomes. | | 1 – 2 PhD | 2 | 2 | Undecided | Yes | | | https://www.science.org/doi/full/10.1126/sciadv.abl5621
https://www.nature.com/articles/s41598-018-25451-3
https://journals.sagepub.com/doi/full/10.1177/1010428317698366 |
| 8 | | Dept of Internal medicine | Cancer Center | AviSahuAI.com | asahu@salud.unm.edu | Computational Biology
Machine learning
Artificial intelligence
Big data
Statistical learning
Immunology | | 2 PhD | 2 | 2 | Yes | Yes | Yes | | https://aacrjournals.org/cancerdiscovery/article/13/3/672/716753/Discovery-of-Targets-for-Immune-Metabolic
https://www.nature.com/articles/s41467-018-04647-1
https://www.embopress.org/doi/full/10.15252/msb.20188323
https://www.nature.com/articles/ncomms9555
https://www.nature.com/articles/nature11247 |
| 9 | | Medicine | Kidney Institute of New Mexico (Research), New Mexico VA Health Care System Research Service | | brwagner@salud.unm.edu | gadolinium, magnetic resonance imaging, nephrology, kidney, NADPH oxidase, MCP-1/CCR2, toxicology, fibrosis, mouse, human subjects, chemistry, transmission electron microscopy, x-ray energy-dispersive spectroscopy, inductively-coupled plasma mass spectroscopy, electron paramagnetic resonance | | 1 PhD | 1 | 1 | Yes | Yes | yes | | https://doi.org/10.1038/s41598-023-28666-1
https://doi.org/10.12788/fp.0258
https://doi.org/10.12788/fp.0199
https://doi.org/10.1152/ajprenal.00456.2020
https://doi.org/10.34067/kid.0000272019
https://doi.org/10.1016/j.jid.2019.03.1145
https://doi.org/10.1016/j.taap.2019.05.009 |
| 10 | | MGM | | https://hsc.unm.edu/directory/chackerian-bryce.html | bchackerian@salud.unm.edu | The Chackerian laboratory is interested in vaccine development; particularly the use of virus particles as platforms for antigen display. Currently, the Chackerian laboratory has projects to develop novel vaccines targeting diverse pathogens (including malaria, Neisseria gonorrhoeae, Sin Nombre virus, and SARS-CoV-2) and vaccines for chronic disease (including dyslipidemia, Alzheimer's, and migraines). | | 0 PhD | 2 | 1 | | Yes | | | https://pubmed.ncbi.nlm.nih.gov/?term=chackerian+b&sort=date |
| 11 | | COP | | https://hsc.unm.edu/pharmacy/research/labs/feng/ | cfeng@unm.edu | Protein dynamics, chemical biology, genetic code expansion, rapid kinetics, electron transfer | 0 | 1 – 2 PhD | 1 | 1 | Yes | | | Yes | https://pubmed.ncbi.nlm.nih.gov/?term=Changjian+Feng |
| 12 | | Internal Medicine (Center for Global Health, Division of Translational Informatics) | Department of Psychiatry and Behavioral Sciences (secondary appointment pending), Department of Computer Science (secondary appointment) | https://vivo.health.unm.edu/display/n25960 | cglambert@salud.unm.edu | Clinical research informatics, cheminformatics & machine learning driven drug, comparative effectiveness research, bioinformatics, computational psychiatry (bipolar disorders, PTSD, suicidality, major mental illness), infectious disease (genomics of malaria and COVID-19), aging/longevity, global health, systems thinking. | | | 1 | 1 | Yes | Yes | | No | https://www.ncbi.nlm.nih.gov/myncbi/1dAdNxivfiO5l/bibliography/public/ |
| 13 | | Internal Medicine | Pathology | | dmarchetti@salud.unm.edu | Translational cancer biology, Circulating Tumor Cells (CTCs) as "seeds" of fatal metastasis, Liquid biopsy, Brain metastasis, Cancer stem cells and CSC signaling pathways, Interplays of cancer dormancy vs. proliferation and metastasis, gene pathways and mechanisms of cancer in circulation promoting the spread to distant organ sites. | | 3 | 3 | 3 | Yes | | | No | Vishnoi M.V., Boral D. , Liu H.N., Sprouse M.L., Yin W., Goswami-Sewell D., Davies M.A., Tetzlaff M., Glitza Oliva I.C., and Marchetti D. Targeting USP7 identifies a metastasis-competent state within BM-resident melanoma CTCs. Cancer Research, 78(18): 5349-5362, 2018. Selected as one of six Breaking Insights - Highlights from recent cancer literature. Cancer Research, 78(20): 5722, 2018.
Sprouse M.L., Welte T., Boral D., Liu H.N., Yin W., Vishnoi M.V., Li L., Goswami-Sewell D., Pei G., Jia P., Glitza-Oliva I.C., and Marchetti D. PMN-MDSCs enhance CTC metastatic properties through reciprocal interactions via ROS/Notch/Nodal Nodal signaling. Int. Journ. Mol. Sciences (Selected for the Special Issue: “Tumor Cell Invasion and Metastasis”), 20(8): 1-21, 2019.
Vishnoi M.V., Liu H.N., Boral D., Yin W., Scamardo A., Hong, D., and Marchetti D. The identification of a TNBC liver metastasis signature by sequential CTC-xenograft modelling. Molecular Oncology, 13(9), 1913-1926, 2019.
Boral D., Liu H.N., Kenney S.R., and Marchetti D. Molecular interplay of dormant bone marrow-resident tumor cells and CTCs in breast cancer. Cancers (Selected for the Special Issue: "Liquid Biopsy: Latest Advances and Future Challenges”), 12: 1626; doi:10.3390/ cancers12061626, 2020. Lecture at the virtual 2020 annual AACR meeting was attended by >1000 attendees worldwide. This work was also highlighted in the Association of American Cancer Institutes (AACI) newsletter which was made available to all cancer centers in the US, or aired as interview on KOB/NBC TV channel. |
| 14 | | Internal Medicine, Center for Global Health | | https://hsc.unm.edu/medicine/departments/internal-medicine/programs-and-centers/global-health/research/pathogen-genomics.html | ddomman@salud.unm.edu | Genomic epidemiology, infectious disease, global health, cholera, SARS-CoV-2, antimicrobial resistance, microbiology | | 1 | 1 | 1 | Yes | | | Undecided | https://scholar.google.com/citations?hl=en&user=tRP01gUAAAAJ&view_op=list_works |
| 15 | | Neurosciences | | https://hsc.unm.edu/medicine/departments/neurosciences/new_faculty/david-linsenbardt-nd.html | dlinsenbardt@salud.unm.edu | Behavioral Neuroscience
Alcohol and other Substance Use Disorders (i.e. 'Addiction')
Prenatal alcohol/drug exposure
Extracellular Electrophysiology
Molecular and Population Genetics | | | 0 | 0 | Yes | | | Yes | https://www.ncbi.nlm.nih.gov/sites/myncbi/david.linsenbardt.1/bibliography/42471045/public/?sort=date&direction=ascending |
| 16 | | Pathology | | https://hsc.unm.edu/medicine/departments/pathology/research/labs/lidke.html | dlidke@salud.unm.edu | Cell signaling
immune receptors
cancer biology
fluorescence microscopy
single molecule imaging
cellular biophysics | 0 | 0 | 1 | 1 | Yes | Yes | | Yes | https://www.molbiolcell.org/doi/10.1091/mbc.E19-09-0548?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
https://www.frontiersin.org/articles/10.3389/fimmu.2020.613286/full
https://www.cell.com/cell/fulltext/S0092-8674(17)31066-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867417310668%3Fshowall%3Dtrue
https://www.molbiolcell.org/doi/10.1091/mbc.E17-06-0350?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed |
| 17 | | Pathology | | https://hsc.unm.edu/medicine/departments/pathology/research/labs/bearer.html | elaine.bearer@gmail.com | Neural activity under different circumstances--Alzheimer's disease, substance use disorders, early life adversity , and life=threatening fear leading to anxiety disorders. | MS | 2 | 2 | 2 | Yes | Yes | | No | Evolution of brain-wide activity in the awake behaving mouse after acute fear by longitudinal manganese-enhanced MRI.
Uselman TW, Barto DR, Jacobs RE, Bearer EL.
Neuroimage. 2020 Nov 15;222:116975. doi: 10.1016/j.neuroimage.2020.116975. Epub 2020 May 28.
Decoupling the Effects of the Amyloid Precursor Protein From Amyloid-β Plaques on Axonal Transport Dynamics in the Living Brain.
Medina CS, Uselman TW, Barto DR, Cháves F, Jacobs RE, Bearer EL.
Front Cell Neurosci. 2019 Dec 3;13:501. doi: 10.3389/fncel.2019.00501. eCollection 2019. PMID: 31849608
Herpes Simplex Virus, Alzheimer's Disease and a Possible Role for Rab GTPases.
Bearer EL, Wu C.
Front Cell Dev Biol. 2019 Aug 7;7:134. doi: 10.3389/fcell.2019.00134. eCollection 2019. PMID: 31448273 |
| 18 | | Department of Pharmaceutical Sciences | -Center for Native Environmental Health Equity Research
-METALS Superfund Research Program
-Department of Civil, Construction & Environmental Engineering, School of Engineering, UNM | https://hsc.unm.edu/directory/elhayek-eliane.html | eelhayek@salud.unm.edu | Asthma pathogenesis and its response to environmental agents; rethinking approaches in biogeochemistry to understand bioavailability and health exposure; community-driven agricultural research for metals exposure | | Maybe 1 MS | 1 | 1 | Yes | | | Yes | -El Hayek, E., Castillo, E., In, J., Parra, A., Garcia, M., Cerrato, J., Brearley, A., Gonzalez-Estrella, J., Herbert, G., Bleske, B., Benavidez, A., Hsiao, H., Yin, L., Campen, M., Yu, X. (2022). Photoaging of polystyrene microspheres causes oxidative alterations to surface physicochemistry and enhances airway epithelial toxicity. Toxicological Sciences. Under revision.
-El Hayek, E., Medina, S., Guo, J., Noureddine, A., Zychowski, K., Hunter, R., Velasco, C., Wiesse, M., Olguin, A.; Brinker, C. J., Brearley, A., Spilde, M., Howard, T., Lauer, F., Herbert, G., Ali, S., Burchiel, S., Campen, M., and Cerrato, J. (2021) Uptake and toxicity of respirable carbon-rich uranium-bearing particles: insights into the role of particulates in uranium toxicity. Environmental Science and Technology, 55 (14), 9949-9957 |
| 19 | | Department of Neurosciences | | | etuncozcan@salud.unm.edu | My research aims to understand how neural circuits and gene networks react to stressful experiences that produce lasting changes in the brain, how such changes can predict adaptive and maladaptive behaviors, and thereafter modulate these changes to prevent and reverse neuropsychiatric disease-like states. The hippocampus has been implicated repeatedly in behavioral responses to stress, antidepressant action, and the pathophysiology of mood disorders, as well as in learning and memory. However, in addition to its effects on the hippocampus, chronic stress affects numerous other brain areas involved in cognition, emotion, and motivation. Thus, the complex effects of experience on brain function cannot be explained by focusing on only one brain region but must incorporate the effects of experience on neural circuits across different brain regions. Therefore, my interim goal is to define the circuit dynamics and cell-type specific transcriptional changes that control differential information processing in mature and immature dentate gyrus neurons in the contexts of antidepressant treatment and stress. Consequently, I will construct a foundational functional model of the dentate gyrus circuitry as it evolves with experience, followed by a detailed cell-type-specific input/output map of the dentate gyrus with various behavioral and molecular phenotypes. This research will set the stage for my lab to manipulate individual neural circuits in a subtype- and projection-specific manner and address the synaptic-, cellular- and circuit-level underpinnings of neuropsychiatric diseases. My long-term goals are to identify novel targets for treating stress-related disorders and to define the heterogeneity in patient populations that predict variable responses to treatment. | | No MS
No PhD | 0 | 1 PhD, 1 MS | Yes | Yes | Yes | | https://pubmed.ncbi.nlm.nih.gov/?term=elif+tunc-ozcan
https://pubmed.ncbi.nlm.nih.gov/31434877/
https://pubmed.ncbi.nlm.nih.gov/34936033/
https://pubmed.ncbi.nlm.nih.gov/35551462/
https://pubmed.ncbi.nlm.nih.gov/36596594/ |
| 20 | | Internal Medicine | Division of Gastroenterology and Hepatology | https://vivo.health.unm.edu/display/n620464620 | ecastillo@salud.unm.edu | Mucosal Immunology, Metabolic diseases, Microplastics and GI health, Heavy Metal exposure and GI health | | 1 PhD | 1 | 2 | Yes | Yes | Yes | | https://www.biorxiv.org/content/10.1101/2023.06.29.547119v1
https://www.biorxiv.org/content/10.1101/2023.06.02.542598v1
https://pubmed.ncbi.nlm.nih.gov/35629938/
https://pubmed.ncbi.nlm.nih.gov/34374750/ |
| 21 | | Internal Medicine | UNM Cancer Cetner; AIM CoBRE | | eprossnitz@salud.unm.edu | Cancer, Metabolism, drug development, estrogen signaling | 0 | 1 | 0 | 1 | Yes | Yes | | No | 1. Sharma G, Hu C, Staquicini DI, Brigman JL, Liu M, Mauvais-Jarvis F, Pasqualini R, Arap W, Arterburn JB, Hathaway HJ, Prossnitz ER. Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes. Sci Transl Med. 2020;12(528). PMC7083206.
2. Revankar CM, Bologa CG, Pepermans RA, Sharma G, Petrie WK, Alcon SN, Field AS, Ramesh C, Parker MA, Savchuk NP, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER. A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling. Cell Chem Biol. 2019;26(12):1692-702 e5. PMC6925632. |
| 22 | | Radiology | | | eriktaylor@salud.unm.edu | Medical imaging, MRI, image processing, machine learning | No | No | 1 | 1 | Yes | | | Undecided | Aging-induced microbleeds of the mouse thalamus compared to sensorimotor and memory defects
Y Wang, E Taylor, B Zikopoulos, F Seta, N Huang, JA Hamilton, ...
Neurobiology of Aging 100, 39-47, 2021
The brains of aged mice are characterized by altered tissue diffusion properties and cerebral microbleeds
EN Taylor, N Huang, J Wisco, Y Wang, KG Morgan, JA Hamilton
Journal of Translational Medicine 18 (1), 1-11, 2020
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02441-6
Biophysical Journal 116 (3), 286a, 2019
MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits
E Taylor, N Huang, J Bodde, A Ellison, R Killiany, MM Bachschmid, ...
Journal of translational medicine 16 (1), 1-11, 2018
Association between tumor architecture derived from generalized Q-space MRI and survival in glioblastoma
GRJ Taylor Erik, Ding Y, Zhu S, Cheah E, Alexander P, Lin L, Aninwene Ii GE ...
Oncotarget 16296, 2017
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522030/ |
| 23 | | Neurosciences | Neuroscience | https://hsc.unm.edu/directory/valenzuela-fernando.html | fvalenzuela@salud.unm.edu | Characterization of the effects of alcohol on neurotransmission in different regions of the brain, with particular emphasis on the developmental effects of ethanol. We use a variety of state-of-the-art approaches, including electrophysiological (including optogenetics), histological, and behavioral techniques. | | | 1 | 1 | Yes | Yes | | No | https://pubmed.ncbi.nlm.nih.gov/33462326/
https://pubmed.ncbi.nlm.nih.gov/31689422/
https://pubmed.ncbi.nlm.nih.gov/29691979/
https://pubmed.ncbi.nlm.nih.gov/29753864/ |
| 24 | | Internal Medicine | Department of Internal Medicine, Division of Molecular Medicine
UNM Comprehensive Cancer Center | | hufan@salud.unm.edu | genome stability maintenance, Cockayne syndrome, premature aging, neuro-degeneration, Notch pathway inhibitor, combinational cancer therapy, PARP1, CSB and oxidative stress. | | Maybe 0 – 1 MS
Maybe 0 – 1 PhD | 1 | 1 | Yes | Yes | Yes | | https://www.ncbi.nlm.nih.gov/myncbi/1fuRdaoI1mdEmy/bibliography/public/ |
| 25 | | Neurosciences | | https://hsc.unm.edu/directory/weick-jason.html | jpweick@salud.unm.edu | We study neuronal development and plasticity in multiple neurological disorders (FASD, AD) using human pluripotent stem cells, organoids, electrophysiology, single cell RNA-sequencing, and many other methods. | 1 | 1 | 2 | 1 | Yes | Yes | | Undecided | https://pubmed.ncbi.nlm.nih.gov/?term=weick+jason&sort=date&size=100 |
| 26 | | Cell Biology and Physiology | | https://hsc.unm.edu/directory/naik-jay.html | jnaik@salud.unm.edu | vascular biology, membrane cholesterol, calcium signaling | | 0 PhD | 1 | 1 | Yes | Undecided | | | Single-cell transcriptomic heterogeneity between conduit and resistance mesenteric arteries in rats.
Anderson JR, Morin EE, Brayer KJ, Salbato S, Gonzalez Bosc LV, Kanagy NL, Naik JS.
Physiol Genomics. 2023 Apr 1;55(4):179-193. doi: 10.1152/physiolgenomics.00126.2022. Epub 2023 Mar 13.
Hydrogen sulfide-induced vasodilation mediated by endothelial TRPV4 channels.
Naik JS, Osmond JM, Walker BR, Kanagy NL.
Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1437-H1444. doi: 10.1152/ajpheart.00465.2016. Epub 2016 Oct 7. |
| 27 | | Pathology | Cancer Center | https://hsc.unm.edu/medicine/departments/pathology/research/labs/gillette.html | jgillette@salud.unm.edu | Our lab studies how cell communication within the bone marrow microenvironment serves to regulate healthy and malignant cells. Currently, we are focused on the role of the tetraspanin family of membrane scaffold proteins and their regulation of quiescence and chemoresistance signaling of hematopoietic/leukemic cells. | | 1 PhD | 1 | 1 | Yes | Yes | | Yes | https://pubmed.ncbi.nlm.nih.gov/34534447/
https://pubmed.ncbi.nlm.nih.gov/32203165/ |
| 28 | | Pharmaceutical Sciences | | https://vivo.health.unm.edu/display/n3385 | kliu@salud.unm.edu | Metal toxicity and carcinogenesis, environmental cancer, DNA repair, whole genome sequencing | | 1 | 1 | 1 | Yes | | | | https://www.oncotarget.com/article/12613/ |
| 29 | | internal medicine | center for global health | https://hsc.unm.edu/directory/cassano-jingyue-j.html | jjia@salud.unm.edu | cell respnse to stress
lysosome
stress granule
autophagy
cell biology
molecular biology | | 1 PhD | 2 | 2 | Yes | Yes | yes | | Jia J., Wang F., Bhujabal Z., Peters R., Mudd M., Duque T., Allers L., Javed R., Salemi M., Behrends C., Phinney B., Johansen T., Deretic V. Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage. J Cell Biol. 2022 Nov 7; 221(11): e202207091.
Jia, J., Bissa, B., Brecht, L., Allers, L., Choi, S., Gu, Y., Zbinden, M., Burge, M.,Timmins, G., Hallows, K.,Behrends, C., Deretic, V. (2020). AMPK, a key regulator of metabolism and autophagy, is activated by lysosomal damage via a novel galectin-directed ubiquitin signal transduction system. Molecular Cell. Molecular Cell 77, 1-19.
Jia, J., Claude-Taupin, A., Gu, Y., Choi, S., Peters, R., Bissa, B., Mudd, M., Allers, L., Pallikkuth, S., Lidke, K., Salemi, M., Phinney, B., Mari, M., Reggiori, F., Deretic, V. (2020). Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal. Developmental Cell, 52(1), 69-87.
Jia, J., Abudu, Y.P., Claude-Taupin, A., Gu, Y., Kumar, S., Choi, S.W., Peters, R., Mudd, M.H., Allers, L., Salemi, M., et al. (2018). Galectins Control mTOR in Response to Endomembrane Damage. Molecular Cell 70, 120-135.e8. |
| 30 | | Neurosciences | | https://hsc.unm.edu/medicine/departments/neurosciences/lab-pages/jlb-lab/ | jbrigman@salud.unm.edu | Traditionally, studies in rodents utilize behaviors that focus on their strengths (digging, smelling, navigating). While these approaches have yielded a wealth of data, they differ greatly from how we measure cognitive function n humans. A major goal of the lab is to develop and validate new assays for investigating behavioral outcomes that can be more directly compared to clinical data. Beginning in 2001 I have worked to develop and refine tasks utilizing touchscreen approaches to screen learning, memory and executive control behaviors. This work helped establish the utility of the mouse in executive function research and led to the wider adoption of touchscreen operant paradigms for high-throughput screening. For the past 10 years my lab has integrated in vivo recording of the activity of cortical neurons and local field potentials during these tasks in vivo to help us better understand how different brain regions mediate specific behaviors. More recently, we have been involved in a multi-university study to compare neural activity associated with specific behavior in both rodents and humans to test the utility of rodent behavioral data in therapeutic target development. | 1 | 1 | 2 | 1 | Yes | | | Undecided | https://pubmed.ncbi.nlm.nih.gov/?term=Brigman+J+%5BAuthor%5D&filter=years.2005-2021&size=50 |
| 31 | | Molecular Genetics and Microbiology | CIDI Signature Program, AIM Center, Cancer Center | https://hsc.unm.edu/directory/cannon-judy.html | jucannon@salud.unm.edu | My laboratory is interested in studying T cell immune responses to infection, focusing on how movement of T cells affects immune clearance. We focus on immune responses in the lung, including T cell response to influenza infection, and also whether E-cigarette exposures affect lung immunity. We use a combination of fluorescence imaging including two photon microscopy, confocal and light sheet microscopy, as well as flow cytometry and animal models to understand how T cells clear infection in specialized tissues such as lung. | 1 | 1 | 1 | 1 | Yes | Yes | | Yes | https://pubmed.ncbi.nlm.nih.gov/31263465/
https://pubmed.ncbi.nlm.nih.gov/29044117/
https://pubmed.ncbi.nlm.nih.gov/26990103/ |
| 32 | | Internal medicine | Division of Gastroenterology | | jgin@salud.unm.edu | 1) WNT and Hedgehog signaling in stem cells to promote regeneration in human intestinal organoids.
2) role of enteroendocrine and goblet cells in intestinal injury
3) differentiation of small bowel stem cells in celiac disease and the role of IgA in minimizing the effects of gluten in the gut | 0 | Maybe 1 MS
Maybe 1 PhD | 2 | 1 | Yes | Yes | | Yes | https://pubmed.ncbi.nlm.nih.gov/34327199/
https://pubmed.ncbi.nlm.nih.gov/33089106/
https://pubmed.ncbi.nlm.nih.gov/30200426/
https://pubmed.ncbi.nlm.nih.gov/36313534/ |
| 33 | | Department of Anesthesiology and Critical Care, School of Medicine | | | junebryan.delapena@wisc.edu | I am an incoming Assistant Professor in the Department of Anesthesiology and Critical Care, School of Medicine, at the University of New Mexico, and I am passionate about developing safer and non-addictive (non-opioid) analgesics for people suffering from chronic pain.
I am using a multifaceted approach to research the molecular mechanisms underlying chronic pain, including high-throughput next-generation sequencing, advanced molecular biology techniques, pharmacological tools, and animal models.
I am also committed to mentoring students and providing them with the skills and knowledge they need to make a real impact in the world. If you are a motivated and passionate student who is interested in research, I would love to have you join my lab. In my lab you can learn cutting-edge technology and use them to research the mechanisms of disease, explore your creativity by testing novel ideas, establish your portfolio towards your long-term goals, and most importantly make an impact in the lives of people with chronic pain. We will create a collaborative and supportive environment where everyone is encouraged to learn, make mistakes, grow, and have fun!
If you are interested, please feel free to reach out to me at junebryan.delapena@wisc.edu.
I look forward to hearing from you. See you at UNM! | | 1 – 2 MS
1 – 2 PhD | 1 - 2 Phd, 1 - 2 MS | 1 - 2 Phd, 1 - 2 MS | Yes | Yes | Yes | | Full list of publications is available here: https://scholar.google.com/citations?user=zfl74V8AAAAJ&hl=en |
| 34 | | Emergency Medicine | Chemical and Biological Engineering | https://scholar.google.com/citations?user=AKcpej8AAAAJ&hl=en | jtbaca@salud.unm.edu | Breath-based testing, Minimally-invasive diagnostics, wearable sensors, Point of care testing, machine learning | 0 | 1 | 1 or 2 | 1 or 2 | Yes | | | Undecided | https://www.nature.com/articles/s42003-018-0170-z
https://www.mdpi.com/1424-8220/15/4/8605/htm
https://onlinelibrary.wiley.com/doi/pdf/10.1002/emp2.12390 |
| 35 | | Anesthesiology & Critical Care Medicine | Neuaroscience | https://hsc.unm.edu/medicine/departments/anesthesiology/research/meet-researchers.html | khigh@salud.unm.edu | My overall research career aim is to stop pain, through pursuit of pain relief mechanisms including HDAC5 epigenetic alterations. We have also developed therapies to test chronic neuropathic and chemotherapy induced pain models. We have patented two non-opioid small single chain (scFv) antibodies that significantly inhibit targets upregulated in chronic neuropathic pain. Single dose of one antibody returns pain-, anxiety-, and depression-like behaviors to baseline in orofacial and sciatic neuropathic, chemotherapy induced, and back pain. Human donor nervous tissue is examined as well as the mouse chronic pain models. | | 1 PhD | 1 | 1 | Yes | Yes | | | https://www.sciencedirect.com/science/article/pii/S2452073X21000088
https://pubmed.ncbi.nlm.nih.gov/32898676/
https://www.frontiersin.org/articles/10.3389/fphys.2020.00440/full
PMID: 33727771 doi: 10.3748/wjg.v27.i9.794 |
| 36 | | | College of Nursing | https://vivo.health.unm.edu/display/n865808269 | kzychowski@salud.unm.edu | toxicology, endothelial barrier integrity, inflammation, extracellular vesicles, air pollution, public health, preclinical studies, clinical and translational studies | 1 | 1 | 1 | 1 | Yes | Yes | | Undecided | https://link.springer.com/article/10.1186/s12989-020-00361-3
https://www.sciencedirect.com/science/article/abs/pii/S2468748018300298
https://www.mdpi.com/2075-1729/11/11/1223 |
| 37 | | Molecular Genetics and Microbiology | | www.frietzelab.com | kfrietze@salud.unm.edu | antibody responses to infectious diseases, vaccines against Chlamydia trachomatis, vaccines against opioids | 0 | 1 | 1 | 1 | Yes | Yes | | Undecided | https://pubmed.ncbi.nlm.nih.gov/34358143/
https://pubmed.ncbi.nlm.nih.gov/33008118/
https://pubmed.ncbi.nlm.nih.gov/32968007/ |
| 38 | | Internal Medicine | Epidemiology, Biostatistics, and Preventive Medicine | | pagek@salud.unm.edu | Epidemiology, Biostatistics, infectious disease, substance use | 1 | 1 | 1 | 1 | Yes | | | No | https://www.nejm.org/doi/full/10.1056/NEJMoa2023345
https://www.sciencedirect.com/science/article/abs/pii/S0376871621000223
https://www.sciencedirect.com/science/article/pii/S1551714421000902
https://academic.oup.com/ofid/article/7/4/ofaa092/5805487?login=true
https://journals.lww.com/jhqonline/Abstract/2021/04000/Improving_Emergency_Access_to_Human.3.aspx
https://www.sciencedirect.com/science/article/pii/S1551714419305749 |
| 39 | | Molecular Genetics & Microbiology | BBHI and Neurology | https://hsc.unm.edu/directory/bhasker-kiran.html | kbhaskar@salud.unm.edu | Alzheimer's disease and related dementia. Neuroinflammation/neuroimmunology. Tau and tauopathies. Alzheimer's vaccines. | No | Maybe 0 – 1 PhD | 1-2 | 1-2 | Yes | Yes | | Yes | https://www.ncbi.nlm.nih.gov/myncbi/kiran.bhaskar.1/bibliography/public/ |
| 40 | | Cell Biology and Physiology | | https://hsc.unm.edu/directory/gonzalez-bosc-laura.html | lgonzalezbosc@salud.unm.edu | Vascular physiology, cell signaling, inflammation, pulmonary hypertension, hypoxia | 0 | Maybe 1 MS
Maybe 1 PhD | 1 | 1 | Yes | Undecided | | No | https://pubmed.ncbi.nlm.nih.gov/32997513/ |
| 41 | | Neurosciences | Center for brain recovery and repair | https://hsc.unm.edu/directory/cunningham-leeanna.html | leeanna@salud.unm.edu | Adult hippocampal neurogenesis | | 0 PhD | 1 | 1 | Yes | No | | Yes | Functional and Structural Correlates of Impaired Enrichment -Mediated Adult Hippocampal Neurogenesis in a Mouse Model of Prenatal Alcohol Exposure. Brain Plasticity 202 Dec 29; 6 (1).
PMID: 33680847 PMCID: PMC7902080
https://www.semanticscholar.org/paper/Functional-and-Structural-Correlates-of-Impaired-in-Gustus-Li/468b9f8384a5774a435fe10acfe999ec909f7408 |
| 42 | | Pathology | Department of Pathology UNMCCC member | https://hsc.unm.edu/medicine/departments/pathology/research/labs/steinkamp.html | msteinkamp@salud.unm.edu | My research interests lie in understanding how complex ErbB receptor interactions promote cell growth and survival in ovarian cancer. Testing the efficacy of anti-ErbB antibodies for ovarian cancer treatment has driven my interest in the tumor microenvironment and how immune cells, particularly tumor-associated macrophages, influence response to cancer therapies. While a good deal is known about how tumor cells respond to treatments in vitro, there is often a disparity between these responses and what is seen in clinical trials. Much of the difference comes from the heterogeneity of the tumor population and the complexity of the tumor microenvironment. Models that can begin to understand this complexity are extremely important for translational research. To examine patient heterogeneity in response to therapy, I have developed patient-derived xenograft (PDX) models from primary spheroids isolated from the malignant ascites fluid of ovarian cancer patients during cytoreductive surgery. To better understand the interactions between human cancer cells and human immune cells in vivo, we have established PDX tumors in mice with engrafted human CD34+ hematopoietic stem cells that create a “humanized” immune system. I am using these models to understand both the direct signaling responses as well as the immune responses to anti-ErbB therapies. I am also interested in developing heterotypic spheroid models to explore the dynamics of antibody-dependent cellular phagocytosis (ADCP) in 3D using live cell light sheet microscopy. | none | Maybe 1 PhD | none | one | Yes | | | No | 1. Steinkamp M.P.*, K.K. Winner, S. Davies, C. Muller, Y. Zhang, R.M. Hoffman, A. Shirinifard, M. Moses, Y. Jiang, and B.S. Wilson. (2013) Ovarian tumor attachment, invasion, and vascularization reflect unique microenvironments in the peritoneum: insights from xenograft and mathematical models. Front Oncol 3: 97. PMID: 24379439. *shared first author
2. Davies, S., A. Holmes, L. Lomo, M.P. Steinkamp, H. Kang, C.Y. Muller, and B.S. Wilson. (2014) High incidence of erbb3, erbb4, and met expression in ovarian cancer. Int J Gynecol Pathol. 33:402-10. PMID: 24901400
3. Steinkamp M.P., S.T. Low-Nam, S. Yang, K.A. Lidke, D.S. Lidke, and B.S. Wilson (2014) Erbb3 is an active tyrosine kinase capable of homo- and heterointeractions. Molecular and Cellular Biology. 34:965-977. PMID: 24379439
4. Kanigel Winner, K.*, M.P. Steinkamp*, R. J. Lee, M. Swat, C.Y. Muller, M.E. Moses, Y. Jiang, B.S. Wilson, (2016) Spatial modeling of drug delivery routes for treatment of disseminated ovarian cancer. Cancer Research, 76:1320-34. PMID: 26719526. *shared first author. |
| 43 | | Biochemistry and Molecular Biology | | labmccormick.org | mmccormick@salud.unm.edu | Biology of Aging; Machine Learning. | | 0 | 1 | 1 | Yes | | | Yes | https://www.sciencedirect.com/science/article/pii/S2468501120300201
https://advances.sciencemag.org/content/advances/6/32/eaba1306.full.pdf
https://www.sciencedirect.com/science/article/abs/pii/S1550413120300127
https://www.sciencedirect.com/science/article/pii/S2468501119300495 |
| 44 | | Chemistry and Chemical Biology | | https://chemistry.unm.edu/people/faculty/profile/matthew-aronoff.html | aronoff@unm.edu | Chemical biology of the extracellular matrix in cancer and diabetes. | | Maybe 0 – 1 PhD
Maybe MS | 0-1 | 0-1 | Yes | Yes | Yes | | Aronoff MR, Hiebert P, Hentzen NB, Werner S, Wennemers H. Imaging and targeting LOX-mediated tissue remodeling with a reactive collagen peptide. Nat Chem Biol. 2021 Aug;17(8):865-871. doi: 10.1038/s41589-021-00830-6. Epub 2021 Jul 12. PMID: 34253910. |
| 45 | | BMB | | https://hsc.unm.edu/medicine/departments/biochemistry/research/liu.html | meilianliu@salud.unm.edu | Adipocyte physiology and immunometabolism | No | 1 PhD | 1 | 1 | Yes | Yes | | Yes | https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/ |
| 46 | | Molecular Genetics and Microbiology | | https://hsc.unm.edu/directory/mandell-michael.html | mmandell@salud.unm.edu | The goal of the Mandell laboratory is to understand how cells coordinate responses to intracellular threats with a focus on retroviral infection. In particular, we study members of the TRIM family of proteins. There are more than 70 TRIMs in the human genome, many of which function to protect cells from viral infection. As antiviral molecules, TRIMs can both directly interfere with viral life cycles and can function as key regulators of innate immunity. Our studies revealed a novel, yet highly conserved, action of TRIMs in another cytoprotective pathway: autophagy. Autophagy is a degradative pathway responsible for the removal of unnecessary and/or potentially dangerous cytoplasmic contents including viruses. Autophagy also has emerging roles in controlling innate immunity. We have shown that TRIMs can control when the cell ‘turns on’ autophagy and can also determine which cellular components are selectively targeted for autophagic removal. Thus, TRIM proteins are positioned as the ‘ringleaders’ of cellular antiviral and innate immune functions. We are working to uncover how TRIMs coordinate these actions.
Our current studies are focused on the HIV-1 restriction factor TRIM5. We have shown that TRIM5 biochemically interacts with multiple components of the autophagy machinery and assembles them into functional complexes. We recently connected these autophagy-related functions of TRIM5 to its actions in antiviral defense. We found that TRIM5 leverages the autophagy machinery to promote antiviral signaling and the establishment of a broadly antiviral state. In this setting, we identified a novel role for the autophagy machinery in scaffolding the assembly of active TRIM5 signaling structures which is in contrast the typical degradative actions of the autophagy pathway.
We are using cell biological, immunological, and proteomic approaches to understand the mechanisms underlying how autophagy contributes to TRIM5’s actions in transducing antiviral signaling. We anticipate that these experiments will advance our understanding of how cells respond to viral infection and reveal novel functions of TRIM5 while also enabling an improved understanding of how autophagy works in mammalian cells. | | | 0 | 0 | Yes | | | Undecided | Saha B, Mandell MA. The retroviral restriction factor TRIM5 regulates mitochondrial quality control. 2022. Autophagy Journal. PMID: 35659190.
Saha B, Salemi M, Williams GL, Oh S, Paffett ML, Phinney B, Mandell MA. (2022). Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy. Cell Reports 39:110797. PMID: 35545034.
Saha B, Chisholm D, Kell AM, Mandell MA (2020) A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α. PLoS Pathog 16(10): e1009017. https://doi.org/10.1371/journal.ppat.1009017
Kehl SR, Soos BA, Choi SW, Herren AW, Johansen T, Mandell MA (2019). TAK1 converts Sequestosome 1/p62 from an autophagy receptor to a signaling platform. EMBO Rep. 2019 Jul 25:e46238
Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V. TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation. J Cell Sci. 2016 Oct 1;129(19):3562-3573.
Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Munch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V. TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition. Dev Cell. 2014 Aug 5. pii: S1534-5807(14)00402-X. doi: 10.1016/j.devcel.2014.06.013. |
| 47 | | Molecular Genetics & Microbiology | | https://hsc.unm.edu/directory/ozbun-michelle.html | mozbun@salud.unm.edu | Mechanistic role of MEK signaling in regulating HPV oncogene expression during viral infections and precancers. Topical drug formulation for treating human papillomavirus (HPV) infections based on a recent publication from graduated PhD student, Dr. Adrian Luna (https://pubmed.ncbi.nlm.nih.gov/33481911/ ).
This is a collaboration with Dr. Jason McConville, College of Pharmacy (https://innovations.unm.edu/jason-t-mcconville-ph-d/)
Mechanistic role of MEK signaling in HPV-induced cancers. We are investigating whether MEK inhibitors can sensitize cervical cancer cells to chemotherapy or radiation treatment.
Both projects involve cell culture, three-dimensional organotypic (raft) epithelial cell cultures, biochemistry, cell biology and animal studies | 0 | 0 – 1 PhD | 1 | 1 | Yes | Yes | | No | https://pubmed.ncbi.nlm.nih.gov/33481911/
https://pubmed.ncbi.nlm.nih.gov/33422988/ |
| 48 | | Molecular Genetics and Microbiology | | | mrosaslemus@salud.unm.edu | Metabolism of infectious diseases focused on the viral RNA-capping metabolism, host S-adenosylmethionine and ATP production | | 1 PhD | 1 | 1 | Yes | Yes | Yes | | https://www.science.org/doi/abs/10.1126/scisignal.abe1202
https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2022.36.S1.R6257
https://scholar.google.com/citations?view_op=view_citation&hl=en&user=uPpKDOgAAAAJ&sortby=pubdate&citation_for_view=uPpKDOgAAAAJ:ULOm3_A8WrAC |
| 49 | | Cell Biology & Physiology | | | nkanagy@salud.unm.edu | endothelial cell biology, vascular physiology, translational research | 0 | 0 | 0 | 0 | Undecided | | | | https://journals.physiology.org/doi/10.1152/ajpheart.00672.2019 |
| 50 | | Biochemistry and Molecular Biology | Internal Medicine | | nzaidman@salud.unm.edu | Adhesion GPCRs; Renal Physiology; Epithelial Physiology | | 1 – 2 PhD
Maybe MS | 1-2 | 1-2 | Yes | | | Yes | https://journals.physiology.org/doi/abs/10.1152/ajprenal.00272.2022
https://pubmed.ncbi.nlm.nih.gov/33004624/
https://pubmed.ncbi.nlm.nih.gov/34261071/ |
| 51 | | Cell Biology and Physiology | | https://hsc.unm.edu/directory/jernigan-nikki.html | njernigan@salud.unm.edu | Vascular Physiology
Pulmonary Hypertension
Metabolic Syndrome
acid-sensing ion channel | | 1 PhD | 1 | 1 | Undecided | Yes | | No | https://www.ncbi.nlm.nih.gov/myncbi/nikki.jernigan.1/bibliography/public |
| 52 | | Neurosciences | | https://hsc.unm.edu/directory/mellios-nikolaos.html | nmellios@salud.unm.edu | Role of circular RNAs in brain development, function, and neurological and psychiatric disorders. | 0 | 1 | 1 | 1 | Yes | Yes | | No | https://www.nature.com/articles/s41380-020-0653-4
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3744423
https://www.frontiersin.org/articles/10.3389/fnins.2020.581895/full |
| 53 | | Biochemistry and Molecular Biology | UNM Comprehensive Cancer Center | ponomarovalab.com | oponomarova@salud.unm.edu | Architecture and function of metabolic pathways; Metabolomics; Systems-level understanding of metabolic disease; Diet-genotype interactions; C. elegans; Bacteria; Automated image analysis | | 1 MS
1 PhD | 2 | 2 | Yes | Yes | Yes | | https://scholar.google.com/citations?hl=en&user=1oeqVNMAAAAJ&view_op=list_works&sortby=pubdate |
| 54 | | Pharmaceutical Sciences | | | phall@salud.unm.edu | Staphylococcus aureus, host-pathogen interactions | 0 | 0 PhD | 0 | 0 | No | No | | No | https://pubmed.ncbi.nlm.nih.gov/30718654/
https://pubmed.ncbi.nlm.nih.gov/29222165/
https://pubmed.ncbi.nlm.nih.gov/28377579/ |
| 55 | | Pharmaceutical Sciences | | https://hsc.unm.edu/pharmacy/research/labs/muttil/ | pmuttil@salud.unm.edu | Drug and vaccine formulation development and testing in animal models | Yes | Maybe | one | one | Yes | | | No | https://scholar.google.com/citations?hl=en&user=E7HQQZwAAAAJ&view_op=list_works&sortby=pubdate |
| 56 | | Pathology | Chemical and Biological Engineering | | rgullapalli@salud.unm.edu | Hepatobiliary Cancer, Genomics, Bioinformatics, Systems Biology, Heavy metal toxicology | 0 | 0 | 0 | 0 | Undecided | Undecided | | No | Non-autophagy role of Atg5 and NBR1 in unconventional secretion of IL-12 prevents gut dysbiosis and inflammation.
Merkley SD, Goodfellow SM, Guo Y, Wilton ZER, Byrum JR, Schwalm KC, Dinwiddie DL, Gullapalli RR, Deretic V, Jimenez Hernandez A, Bradfute SB, In JG, Castillo EF. J Crohns Colitis. 2021 Aug 10:jjab144. doi: 10.1093/ecco-jcc/jjab144. Online ahead of print. PMID: 34374750
Ethics of AI in Pathology: Current Paradigms and Emerging Issues.
Chauhan C, Gullapalli RR. Am J Pathol. 2021 Jul 10:S0002-9440(21)00303-5. doi: 10.1016/j.ajpath.2021.06.011. Online ahead of print. PMID: 34252382 Review.
A Deep Learning Convolutional Neural Network Can Differentiate Between Helicobacter Pylori Gastritis and Autoimmune Gastritis With Results Comparable to Gastrointestinal Pathologists.
Franklin MM, Schultz FA, Tafoya MA, Kerwin AA, Broehm CJ, Fischer EG, Gullapalli RR, Clark DP, Hanson JA, Martin DR. Arch Pathol Lab Med. 2021 Apr 15. doi: 10.5858/arpa.2020-0520-OA. Online ahead of print. PMID: 33861314 Free article.
Cadmium exposure activates Akt/ERK Signaling and pro-inflammatory COX-2 expression in human gallbladder epithelial cells via a ROS dependent mechanism.
Sharma P, Caldwell TS, Rivera MN, Gullapalli RR. Toxicol In Vitro. 2020 Sep;67:104912. doi: 10.1016/j.tiv.2020.104912. Epub 2020 Jun 6. PMID: 32512147 |
| 57 | | Neurology | | https://hsc.unm.edu/medicine/departments/neurology/research/labs/poddar.html | rpoddar@salud.unm.edu | Consequences of hyperhomocysteinemia (metabolic disorder) on progression of cerebral stroke and Alzheimer's disease, cell signaling, Glutamate receptors, inflammation with emphasis on neuro-immune communication. | | 1 | | 1 | No | | | No | Jindal et.al (2019) Neurobiol Dis. 127: 287-302.
https://www.sciencedirect.com/science/article/pii/S0969996118303255
Deep et.al. (2019) J. Biol Chem. 294 (29): 11154-11165.
https://www.jbc.org/article/S0021-9258(20)30244-1/fulltext
Rajagopal et.al (2019) J Neurochem. 150 (1): 44-55.
https://onlinelibrary.wiley.com/doi/epdf/10.1111/jnc.14775
Poddar R. (2021) Exp Neurol. Feb, 336: 113541
https://www.sciencedirect.com/science/article/pii/S0014488620303721 |
| 58 | | Radiology | Nuclear Engineering, Cancer Center | https://hsc.unm.edu/directory/selwyn-reed.html | rselwyn@salud.unm.edu | Quantitative imaging characteristics of mild traumatic brain injury and cancer. | 0 | 0 | 0 | 1 | No | | | No | Hong K, Akinwande O, Bodei L, Chamarthy MR, Devlin PM, Elman S, Ganguli S, Kennedy AS, Koo SJ, Ouhib Z, Padia SA, Salem R, Selwyn RG, Yashar CM, Yoo DC, Zaki BI, Hartford AC, Trimmer CK. ACR-ABS-ACNM-ASTRO-SIR-SNMMI practice parameter for selective internal radiation therapy or radioembolization for treatment of liver malignancies. Brachytherapy. 2021 May-Jun;20(3):497-511
Sidebottom RB, Aulwes EF, Freeman MS, Magnelind P, Merrill FE, Noureddine A, Selwyn R, Serda R, Tupa D, Yang Y, Espy M. Gold nanoparticles for tumor detection with proton radiography: optimizing sensitivity and determining detection limits. SPIE Proceedings. March 2021;11659
Manda-Mapalo M, Fine SG, Safadi S, Lee J, Du R, Sussman A, Mishra S, Selwyn RG, Saline JL, Hine WL, Brown-Glaberman U. Breast cancer screening among medically underserved woman in New Mexico: Potential for lower recall rates with digital breast tomosynthesis. J of Woman’s Health. 2020;29(12):1596-1601
McIlwrath SL, Montera MA, Gott KM, Yang Y, Wilson CM, Selwyn R, Westlund KN. Manganese-enhanced MRI reveals changes within brain anxiety and aversion circuitry in rats with chronic neuropathic pain- and anxiety-like behaviors. Neuroimage. 2020 Dec;223. Epub 2020 Sep 6
Hobson N, Polster SP, Cao Y, Flemming K, Shu Y, Huston J, Gerrard CY, Selwyn R, Mabray M, Zafar A, Girard R, Carrion-Penagos J, Fen Chen Y, Parrish T, Zhou XJ, Koenig JI, Shenkar R, Stadnik A, Koskimaki J, Dimov A, Turley D, Carroll T, Awad IA. Phantom validation of quantitative susceptibility and dynamic contrast-enhanced permeability MR sequences across instruments and sites. J Magn Reson Imaging. 2020;51(4):1192-1199.
Maphis NM, Peabody J, Crossey E, Jiang S, Jamaleddin Ahmad FA, Alvarez M, Mansoor SK, Yaney A, Yang Y, Sillerud LO, Wilson CM, Selwyn R, Brigman JL, Cannon JL, Peadbody DS, Chackerian B, Bhaskar K. QB virus-like particle-based vaccine induces robust immunity and protects against tauopathy. NPJ Vaccines. 2019;4(1):1-13.
Brocato TA, Brown-Glaberman U, Wang Z, Selwyn RG, Wilson CM, Wyckoff EF, Lomo LC, Saline JL, Hooda-Nehra A, Pasqualini R, Arap W, Brinker CJ, Cristini V. Predicting breast cancer response to neoadjuvant chemotherapy based on tumor vascular features in needle biopsies. JCI Insight. 2019;4(8).
McCart EA, Thangapazham RL, Lombardini ED, Mog SR, Panganiban RAM, Dickson KM, Mansur RA, Nagy V, Kim SY, Selwyn R, Landauer MR, Darling TN, Day RM. Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury. J Radiat Res. 2017;58(5):636-646. |
| 59 | | | Roberto Ivan Mota Alvidrez |
| Pharmaceutical Sciences | | | rmotaa@hotmail.com | Diabetic vasculopathy
Glucose and lipid metabolism
Atherothrombosis
Molecular Imaging | | 1 MS
1 – 2 MS
2 PhD | 2 | 2 | Yes | Yes | Yes | | 1) https://link.springer.com/article/10.1007/s40139-022-00231-x
2) https://pubmed.ncbi.nlm.nih.gov/34889809/#:~:text=injury%20following%20trauma-,Reduced%20cleavage%20of%20von%20willebrand%20factor%20by%20ADAMTS13%20is%20associated,doi%3A%2010.1097%2FMBC.
3) https://assets.researchsquare.com/files/rs-2188875/v1/01f82c9a-414d-4012-9035-0b6a31fd2f0a.pdf?c=1666878016 |
| 60 | | Neurosciences | | https://hsc.unm.edu/directory/morton-russell.html / https://mortonneurolab.com | ramorton@salud.unm.edu | My lab is interested in the role of spreading depolarization in concussion-like injuries. We use a mouse model of concussions to investigate the physiological and cellular events that occur in the first few minutes following an injury. | 1 | 1 | 1 | 1 | Yes | | | Undecided | https://mortonneurolab.com/publications |
| 61 | | Neurosciences | | | samckenzie@salud.unm.edu | Memory, physiology, epilepsy, synaptic plasticity, hippocampal function | | 1 PhD | 1 | 1 | Yes | Yes | | Yes | https://www.sciencedirect.com/science/article/pii/S0896627321000337
https://www.nature.com/articles/s41467-020-15787-8
https://www.sciencedirect.com/science/article/pii/S0896627317309029 |
| 62 | | Cell Biology and Physiology | | https://hsc.unm.edu/directory/piccirillo-sara.html | SPiccirillo@salud.unm.edu | Brain Tumors, Cancer Genomics, Stem Cells | 0 | Maybe 1 PhD | 1 | Maybe 1 | Yes | Yes | | Yes | https://pubmed.ncbi.nlm.nih.gov/30452544/
https://pubmed.ncbi.nlm.nih.gov/30590711/ |
| 63 | | Pharmaceutical Sciences | Professor and Director of NM-INSPIRES P30 Environmental Health Sciences Core Center | | sblossom@salud.unm.edu | I study how environmental contaminants promote allergic disease and autoimmunity. We use human and mouse cell culture as well as mouse models. Our lab uses flow cytometry, RNA-sequencing, DNA methylation (epigenetics assessments), qPCR, and ELISA based or western blotting techniques to answer our research questions. | | 1 PhD | 3 | 3 | Undecided | Yes | yes | | https://www.ncbi.nlm.nih.gov/myncbi/sarah.blossom.1/bibliography/public/ |
| 64 | | Anesthesiology and Critical Care Medicine | Neurosciences | www.alleslab.com | salles@salud.unm.edu | Chronic pain, ion channels, nociceptors, GPCRs, sensory neurons, dorsal root ganglia, trigeminal ganglia, spinal cord, brain, human samples, exosomes, antibody therapeutics, electrophysiology, calcium imaging | | 1 PhD | 1 | 1 | Yes | Yes | Yes | | https://www.ncbi.nlm.nih.gov/myncbi/dr%20sascha.alles.1/bibliography/public/ |
| 65 | | Internal Medicine / Molecular Medicine | UNM Cancer Center, Associate Director for Shared Resources; Director of Analytical and Translational Genomics Shared Resource | https://unmhealth.org/cancer/research/programs/labs/ness.html | sness@salud.unm.edu | Cellular differentiation and reprogramming, especially involving stem cells and cancer. Regulation of cell programming by oncogenic transcription factors. Cancer genomics, epigenetics and transcriptional regulation. | | 0 PhD | 1 | 1 | No | | | No | https://pubmed.ncbi.nlm.nih.gov/32867110/
https://pubmed.ncbi.nlm.nih.gov/31877778/
https://pubmed.ncbi.nlm.nih.gov/29484115/
https://pubmed.ncbi.nlm.nih.gov/26631070/ |
| 66 | | Internal medicine | Division of Epidemiology, Biostatistics, and Preventive Medicine | | sleng@salud.unm.edu | I am a molecular epidemiologist with extensive expertise in applying “systems epidemiology” approach in understanding the etiology and mechanisms for human diseases including cancer and lung aging. My research contains both dry lab and wet lab components. I have access to data and bio-specimens from large smoker cohort such as Lovelace smokers cohort and the Pittsburgh Lung Cancer SPORE cohort. My wet lab component focuses on biomarker development and translational studies from bedside to benchside to understand potential mechanisms for associations seen at the population level. Currently, I have a whole genome sequencing study to understand the ethnic disparity of liver cancer and a whole genome wide association study to understand genetic determinants for lung aging. We are also running exosome experiment to identify novel lung aging biomarkers. One multi-site collaborative study funded by NIGMS/CTR-IN assesses residential wood smoke exposure using questionnaires and biomarkers with the goal of understanding the pulmonary and cancer risk of household wood smoke exposure. | 1 | 1 | 1 | 1 | Yes | | | Yes | https://www.sciencedirect.com/science/article/pii/S0002937822005877
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058990/
https://link.springer.com/article/10.1007%2Fs00204-020-02678-6 |
| 67 | | Internal Medicine | Center for Global Health | https://hsc.unm.edu/medicine/departments/internal-medicine/programs-and-centers/global-health/research/emerging-viral-pathogens.html | sbradfute@salud.unm.edu | The Bradfute lab studies immunity, host response, and genetics of emerging viral pathogens, including hantaviruses, alphaviruses, filoviruses, and coronaviruses. | 0 | Unknown | 1 | 1 | Yes | | | Yes | https://www.ncbi.nlm.nih.gov/myncbi/1FO46Bi8pKbAh/bibliography/public/ |
| 68 | | Pathology | UNM Comprehensive Cancer Center | http://thekimlab.net | takim@salud.unm.edu | Cancer research / Mechanobiology / Cell and molecular biology / Cancer Metabolism / Cancer immunotherapy | | 1 – 2 PhD | 1 - 2 PhD | 1 - 2 PhD | Yes | Yes | | Undecided | https://www.ncbi.nlm.nih.gov/sites/myncbi/tae-hyung.kim.2/collections/61637063/public/ |
| 69 | | Pathology | | | tburanda@salud.unm.edu | Infectious disease, role of receptor signaling in host cell infection by viruses (Sars-CoV2, hantaviruses) Assay development for sepsis diagnosis. | no | no | 1 | 1 | Yes | Yes | | Yes | https://pubmed.ncbi.nlm.nih.gov/34452463/
Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease
Peter Simons 1 , Yan Guo 2 , Virginie Bondu 1 , Susan L Tigert 3 , Michelle Harkins 4 , Samuel Goodfellow 4 , Cana Tompkins 1 , Devon Chabot-Richards 1 , Xuexian O Yang 5 , Laura Gonzalez Bosc 6 , Steven Bradfute 4 , Daniel A Lawrence 7 , Tione Buranda 1
Integrin activation is an essential component of SARS-CoV-2 infection
Peter Simons, Derek A Rinaldi, Virginie Bondu, Alison M Kell, Steven Bradfute, Diane Lidke, Tione Buranda
https://www.nature.com/articles/s41598-021-99893-7
Integrins as Therapeutic Targets for SARS-CoV-2
Timothy E. Gressett1,2,3, Danielle Nader4, Juan Pablo Robles5, Tione Buranda6*, Steven W. Kerrigan4* and Gregory Bix1,2,3*
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9128570/ |
| 70 | | Cell Biology and Physiology | | https://hsc.unm.edu/directory/resta-tom.html | tresta@salud.unm.edu | Cellular oxidant signaling and mitochondrial dysfunction in pulmonary hypertension.
Regulation of vascular smooth muscle and endothelial function by membrane cholesterol.
Novel mechanisms of vascular regulation. | | 1 PhD | 1 | 1 | Yes | Yes | Yes | | https://pubmed.ncbi.nlm.nih.gov/34487355/
https://pubmed.ncbi.nlm.nih.gov/33076504/
https://pubmed.ncbi.nlm.nih.gov/33076504/
https://pubmed.ncbi.nlm.nih.gov/31945301/
https://pubmed.ncbi.nlm.nih.gov/31264901/
https://pubmed.ncbi.nlm.nih.gov/29373038/
https://pubmed.ncbi.nlm.nih.gov/29101179/
https://pubmed.ncbi.nlm.nih.gov/28666030/ |
| 71 | | Neurosciences | New Mexico Alcohol Research Center
University of New Mexico Comprehensive Cancer Center | Center https://hsc.unm.edu/directory/vue-touyia.html | tvue@salud.unm.edu | Transcription factor control of glial cell fate specification and "homing" to gray matter and white matter in the CNS (R01 NINDS 2022 -2027)
Elucidating the cellular and molecular mechanisms of brain tumor development and migration in pre-clinical mouse models of glioblastoma (UNMCCC Pilot Grants)
Determine impacts of prenatal/neonatal alcohol exposure on glial lineage development, gene expression, and function in the brain (NMARC P50 Center Grant) | | 1 PhD | 1 | 1 | Yes | Yes | Yes | | https://scholar.google.com/citations?hl=en&user=xK9ku0gAAAAJ&sortby=pubdate&scilu=&scisig=AMD79ooAAAAAYnFY_NP4u0RZHKhfUaHfjaExvVjYASzu&gmla=AJsN-F4Ez0JzdfoS130LJ1wh-qRLJJIIE-CINyMw7gKLp4EfiJAW-NW_juAhDdmllu8dac5sp3tv78ON_N3BCnmNqeZzwrmz_4jTmVVT-QMFGXrPNiQS5Xg&sciund=7524423115130462606 |
| 72 | | Internal Medicine | Molecular Medicine | | vpalanisamy@salud.unm.edu | Post-transcriptional gene regulation by RNA-binding proteins and non-coding RNAs in oral cancer. | | 2 PhD | 2 | 2 | Yes | Yes | NO | | https://www.ncbi.nlm.nih.gov/myncbi/viswanathan.palanisamy.1/bibliography/public/ |
| 73 | | Molecular Genetics & Microbiology | | | Vojo Deretic | Autophagy | 0 | 1 | 1 | 1 | | | | | https://scholar.google.com/citations?hl=en&user=_ST_u88AAAAJ&sortby=pubdate&view_op=list_works&authuser=1
https://www.nature.com/articles/s41556-021-00706-w
https://www.sciencedirect.com/science/article/abs/pii/S1074761321000418
https://www.nature.com/articles/s41556-020-0549-1
https://www.sciencedirect.com/science/article/pii/S109727651930958X
https://www.sciencedirect.com/science/article/pii/S1534580719309037 |
| 74 | | BMB | https://hsc.unm.edu/pharmacy/research/areas/cmbm/ | https://sites.google.com/site/xiangxueus/ | xxue@salud.unm.edu | Colorectal Cancer, Inflammatory Bowel Disease, Iron Metabolism, Hypoxia signaling | up to 1 | up to 2 | up to 3 | up to 3 | Yes | Yes | | Yes | https://sites.google.com/site/xiangxueus/publications |
| 75 | | Molecular Genetics & Microbiology | | https://hsc.unm.edu/directory/yang-xuexian.html | xyang@salud.unm.edu | Immunity, autoimmunity, allergy, inflammation, T cell | 1 | Maybe PhD | 1 | 1 | Yes | Undecided | | Yes | https://scholar.google.com/citations?hl=en&user=XKdcw6oAAAAJ&view_op=list_works&sortby=pubdate |
| 76 | | Internal Medicine, div of Epidemiology, Biostatistics, and Preventive Medicine | | | yizhu@salud.unm.edu | Pathway-informed data integration and modeling; biostatistics; environmental risk assessment; health service research; international health | Yes | Yes | 1 | 1 | | | | | National Academies of Sciences, Engineering, and Medicine Committee to Review EPA's TSCA Systematic Review Guidance Document (2021) The Use of Systematic Review in EPA’s Toxic Substances Control Act Risk Evaluations
Nestsiarovich A, Kumar P, Lauve NR, Hurwitz NG, Mazurie AJ, Cannon DC, Zhu Y, Nelson SJ, Crisanti AS, Kerner B, Tohen M, Perkins DJ, Lambert CG. Using Machine Learning Imputed Outcomes to Assess Drug-Dependent Risk of Self-Harm in Patients with Bipolar Disorder: A Comparative Effectiveness Study. JMIR Ment Health. 2021 Apr 21;8(4):e24522. PMID: 33688834 |
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